Research

Androgen receptor signaling in Prostate Cancer

Our research focuses on understanding how androgen receptor (AR) protein complexes contribute to prostate cancer progression and therapy resistance. By dissecting the molecular composition and context-specific interactions of AR complexes, we aim to uncover new regulatory mechanisms and identify therapeutic vulnerabilities. We use proteomics, chromatin profiling, and computational approaches to study how these complexes shape cellular behavior in prostate cancer.

Proteomic insights into early embryonic development

We investigate the earliest stages of mouse and human development using stem cell-based models that mimic key events such as gastrulation, somitogenesis and early lineage specification. Our goal is to understand how cells organize, differentiate, and interact to form complex structures. By integrating molecular biology, imaging, and systems-level analysis, we aim to uncover the regulatory principles that guide embryogenesis.